Yıl:2022   Cilt: 8   Sayı: 2   Alan: Ziraat, Orman ve Su Ürünleri Temel Alanı

  1. Anasayfa
  2. Makale Listesi
  3. ID: 126

Uoropathogenic Escherichia coli chromosomal study of cnf1 and fyuA genes among patients of urinary tract infection in Kirkuk city

Nihad I. TAHA ORCID Icon,Nashwan O. TAPABASHİ ORCID Icon,Safa R. AGA ORCID Icon

The objective of this work was to prepare azo and azo-chalcones derivatives out of 2, 6- diaminopyridine (2, 6-DAP) which has extensive use in the synthesis of pharmaceutical compounds. The azo-diamine (S1-S6) was prepared from the coupling reaction of diazonium salt prepared from various substituted aromatic amines with 2, 6-diaminopyridine. The product (S6) was reacted in basic condition with one equivalent of different substituted aromatic aldehydes in methanol to give ten new azo-chalcones (S7-S16) in good yields. The final products were identified by their physical properties besides their UV-visible, FTIR and 1H NMR spectra. Biological activity of the compounds (S1-S6) was investigated and compounds (S1 and S2) showed high activity against B. subtilis and E. coli .

Anahtar Kelimeler: Azo- Chalcone, 2, 6-Diaminopyridine, diazonium salt, pyridine


Uoropathogenic Escherichia coli chromosomal study of cnf1 and fyuA genes among patients of urinary tract infection in Kirkuk city

The objective of this work was to prepare azo and azo-chalcones derivatives out of 2, 6- diaminopyridine (2, 6-DAP) which has extensive use in the synthesis of pharmaceutical compounds. The azo-diamine (S1-S6) was prepared from the coupling reaction of diazonium salt prepared from various substituted aromatic amines with 2, 6-diaminopyridine. The product (S6) was reacted in basic condition with one equivalent of different substituted aromatic aldehydes in methanol to give ten new azo-chalcones (S7-S16) in good yields. The final products were identified by their physical properties besides their UV-visible, FTIR and 1H NMR spectra. Biological activity of the compounds (S1-S6) was investigated and compounds (S1 and S2) showed high activity against B. subtilis and E. coli .

Keywords: Azo- Chalcone, 2, 6-Diaminopyridine, diazonium salt, pyridine


Atıf İçin

Taha, N. I., Tapabashi, N. O. & Aga, S. R. (2022). Uoropathogenic Escherichia coli chromosomal study of cnf1 and fyuA genes among patients of urinary tract infection in Kirkuk city. Journal of Current Research on Engineering, Science and Technology, 8 (2), 203-212.


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